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malonic ester synthesis

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  • Malonic ester synthesis — The malonic ester synthesis is a chemical reaction where diethyl malonate or another ester of malonic acid is alkylated at the carbon alpha (directly adjacent) to both carbonyl groups, and then converted to a substituted acetic acid.[1] The major …   Wikipedia

  • Acetoacetic ester synthesis — is a chemical reaction where ethyl acetoacetate is alkylated at the α carbon to both carbonyl groups and then converted into a ketone, or more specifically an α substituted acetone. This is very similar to malonic ester synthesis.:MechanismA… …   Wikipedia

  • Malonic acid — Malonic acid …   Wikipedia

  • Ester — For other uses, see Ester (disambiguation). A carboxylic acid ester. R and R denote any alkyl or aryl group, respectively Esters are chemical compounds derived by reacting an oxoacid with a hydroxyl compound such as an alcohol or phenol …   Wikipedia

  • malonic acid — Chem. a white, crystalline, water soluble, dibasic acid, C3H4O4, easily decomposed by heat: used chiefly as an intermediate in the synthesis of barbiturates. [1885 90] * * * ▪ chemical compound also called  Propanedioic Acid        (HO2CCH2CO2H) …   Universalium

  • malonic acid — məˈlōnik , länik noun Etymology: malonic from F. malonique (in acide malonique malonic acid), alteration of malique malic (in acide malique malic acid) more at malic acid : a crystalline dicarboxylic acid CH2(COOH)2 obtained by oxidation of malic …   Useful english dictionary

  • malonic acid — A dicarboxylic acid of importance in intermediary metabolism; an inhibitor of succinate dehydrogenase. SYN: propanedioic acid. * * * ma·lo·nic acid mə lōn ik , län n a crystalline dicarboxylic acid CH2(COOH)2 used esp. in the form of its diethyl… …   Medical dictionary

  • carboxylic acid — Chem. any organic acid containing one or more carboxyl groups. [1900 05; CARBOXYL + IC] * * * Any organic compound with the general chemical formula ―COOH in which a carbon (C) atom is bonded to an oxygen (O) atom by a double bond to make a… …   Universalium

  • Diethyl malonate — Diethyl malonate …   Wikipedia

  • Meldrum's acid — IUPAC name 2,2 Dimethyl 1,3 dioxane 4,6 dione …   Wikipedia

  • Decarboxylation — is a chemical reaction that releases carbon dioxide (CO2). Usually, decarboxylation refers to a reaction of carboxylic acids, removing a carbon atom from a carbon chain. The reverse process, which is the first chemical step in photosynthesis, is… …   Wikipedia

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